Cosmetic Ingredient Hotlist - September 2009 - [D-L]

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• A-C
• D-L
• M-P
• Q-Z

• Datura stramonium L. and its galenical preparations
• Deanol aceglumate (3342-61-8)
• Decamethylenebis (trimethylammonium) salts
• Dextromethorphan (125-71-3) and its salts
• Dextropropoxyphene (469-62-5)
• O,O'-Diacetyl-N-allyl-N-normorphine
• Dialkanolamines, secondary (including, but not limited to diethanolamine (DEA) (111-42-2) and diisopropanolamine (DIPA) (110-97-4))
• 2,4-Diaminophenylethanol and its salts
• 5-(α, β-Dibromophenethyl)-5-methylhydantoin (511-75-1)
• Dibromosalicylanilides
• Dichloroethanes (ethylene chlorides)
• Dichloroethylenes (acetylene chlorides)
• 2,3-Dichloro-2-methylbutane (507-45-9)
• Dichlorosalicylanilides
• Dicoumarol (66-76-2)
• 3-Diethylaminopropyl cinnamate
• Diethyl maleate (141-05-9)
• Diethyl 4-nitrophenyl phosphate (311-45-5)
• Diethyl toluamide (DEET) (134-62-3)
• Diethylene glycol (DEG) (111-46-6)
  • Not permitted in oral or leave-on products (see also "Glycerin")
• Diethylhexyl phthalate (DEHP) (117-81-7)
• Difencloxazine (5617-26-5)
• Digitaline (71-63-6)
• Digitalis purpurea L., all heterosides of
• Dihydrocoumarin (119-84-6)
• Dihydrotachysterol (67-96-9)
• 2,4-Dihydroxy-3-methylbenzaldehyde (6248-20-0)
• 4,4'-Dihydroxy-3,3'-(3-methylthiopropylidene) dicoumarin
• 5,5'-Diisopropyl-2,2'-dimethylbiphenyl-4,4'-diyl dihypoiodite
• Dimethoxane (2,6-dimethyl-1,3-dioxan-4-yl acetate) (828-00-2)
• Dimethylamine (124-40-3)
• 4,6-Dimethyl-8-tert-butylcoumarin (17874-34-9)
• Dimethyl citraconate (617-54-9)
• 7,11-Dimethyl-4,6,10-dodecatrien-3-one (26651-96-7)
  • Permitted at concentrations equal to or less than 2% only as an impurity in methylionones
• Dimethylformamide (68-12-2)
• 1,3-Dimethylpentylamine (105-41-9) and its salts
• Dimethyl sulfoxide (DMSO) (67-68-5)
• 6,10-Dimethyl-3,5,9-undecatrien-2-one (141-10-6)
• Dimevamide (60-46-8) and its salts
• Dinitrophenol isomers (25550-58-7)
• Dioxane (1,4-dioxane) (123-91-1)
• Dioxethedrin (497-75-6) and its salts
• Diphenhydramine (58-73-1) and its salts
• Diphenoxylate hydrochloride (3810-80-8)
• Diphenylamine (122-39-4)
• 5,5-Diphenyl-4-imidazolidone (3254-93-1)
• Diphenylpyraline (147-20-6) and its salts
• Disulfiram (97-77-8)
• Doxylamine (469-21-6) and its salts
• Emetine (483-18-1), its salts and derivatives
• Endrin (72-20-8)
• Ephedrine (299-42-3) and its salts
• Epinephrine (51-43-4)
• 1,2-Epoxybutane (106-88-7)
• Ergocalciferol (50-14-6)
  • Average daily absorption should be equal to or less than 25 μg per day
• Eserine (57-47-6) and its salts
• Estil (305-13-5) and its salts
• Estradiol (50-28-2)
• Estrogens
• Estrone (53-16-7)
• Ethinylestradiol (57-63-6)
• Ethionamide (536-33-4)
• Ethoheptazine (77-15-6) and its salts
• Ethoxyethanol (110-80-5)
• Ethoxyethanol acetate (111-15-9)
• 4-Ethoxyphenol (622-62-8)
• 4-Ethoxy-m-phenylenediamine (5862-77-1) and its salts
• Ethyl biscoumacetate (548-00-5) and salts of the acid
• Ethylenediamine (107-15-3)
• Ethylene oxide (75-21-8)
• Ethyl methacrylate (97-63-2)
  • The label of the cosmetic shall carry a cautionary statement to the effect: "Avoid skin contact."
• Ethyl PABA (benzocaine) (94-09-7)
• Ethylphenacemide (90-49-3)
• β-Eucaine (500-34-5)
• Eucalyptus oil (8000-48-4)
  • Permitted at concentrations equal to or less than 25%
• Fenadiazole (1008-65-7)
• Fenozolone (15302-16-6)
• Fenyramidol (553-69-5)
• Ficus carica leaf absolute (68916-52-9)
• Fluanisone (1480-19-9)
• Fluoresone (2924-67-6)
• Fluoride (16984-48-8) containing substances (including, but not limited to sodium fluoride (1333-83-1, 7681-49-4), calcium fluoride (7789-75-5), stannous fluoride (7783-47-3) and sodium monofluorophosphate (10163-15-2))
  • Not permitted in oral products
• Fluorouracil (51-21-8)
• Formaldehyde (50-00-0)
  • Not permitted in aerosol cosmetics
  • Permitted at concentrations equal to or less than 0.1% in oral products
  • Permitted at concentrations equal to or less than 0.2% in non-oral products as a preservative only
  • Permitted at concentrations equal to or less than 5% in nail hardeners only. Nail hardeners containing formaldehyde must be sold with nail shields, directions for use, and a cautionary statement on the inner and outer labels to the effect: "This product contains formaldehyde which has the potential to cause skin sensitivity."
• Furazolidone (67-45-8)
• Furfuryltrimethylammonium salts
• Furocoumarins (66-97-7), except for naturally occurring in plant extracts
  • Permitted at concentrations less than 1 mg/kg in sun tanning products.
• Galantamine (357-70-0)
• Gallamine triethiodide (65-29-2)
• Glucocorticoids (1524-88-5)
• Glutarimide (1121-89-7) and its salts
• Glutethimide (77-21-4) and its salts
• Glycerin (56-81-5)
  • Manufacturers of oral and leave-on products containing glycerin must ensure the raw material used is within the specifications of an accepted pharmacopoeia with respect to diethylene glycol (DEG) impurities (e.g. Glycerin Official Monograph in the most current edition of the USP)
• Glycyclamide (664-95-9)
• Gold salts (including, but not limited to gold chloride HCl (16903-35-8), gold acetylmethionate (105883-47-4), and gold aspartate/glutamate)
• Guaifenesin (93-14-1)
• Guanethidine (55-65-2) and its salts
• Haloperidol (52-86-8)
• trans-2-Heptenal (18829-55-5)
• Hexachloroethane (67-72-1)
• Hexachlorophene (2,2'-dihydroxy-3,3',5,5'6,6'-hexachlorodiphenylmethane) (70-30-4)
• Hexaethyl tetraphosphate (757-58-4)
• Hexamethonium salts
• Hexapropymate (358-52-1)
• Human origin, substance of (including, but not limited to human placental extracts, human placental enzymes, human placental lipids, human placental protein, human umbilical extract, hydrolyzed human placental protein (73049-73-7), hydrolyzed keratin from human hair, lyophilized human placental extract)
  • Manufacturers using substances of human origin must provide the following information to Health Canada:
    1. source of the substance;
    2. a description of the method of production;
    3. quality control data, particularly those relating to microbial limits (including viruses) and the absence of estrogenic substances;
    4. product labelling.
• Hydrastine (118-08-1) and their salts
• Hydrastinine (6592-85-4) and their salts
• Hydrazides and their salts
• Hydrazine (302-01-2), its derivatives and their salts
• Hydroabietyl alcohol (13393-93-6)
• Hydrofluoric acid (7664-39-3), its normal salts, its complexes and hydrofluorides
• Hydrogen cyanide (74-90-8) and its salts
• Hydrogen peroxide (7722-84-1) (see "Peroxide and peroxide generating compounds")
• Hydrolyzed Hemp seed protein
  • Permitted at concentrations less than 10 μg/g THC (delta-9-tetrahydrocannabinol), as per the Industrial Hemp Regulations
• Hydroquinone (123-31-9)
  • Not permitted in products to be applied on the skin or mucous membranes
• p-Hydroxyanisole (4-methoxyphenol) (150-76-5)
  • Permitted at concentrations equal to or less than 0.02% (after mixing), for professional use only, in artificial nail systems
  • The inner label and the outer label of the cosmetic shall carry statements to the effect: "For professional use only, avoid skin contact, read use directions carefully."
• 11-α-Hydroxypregn-4-ene-3,20-dione (80-75-1) and its esters
• 8-Hydroxyquinoline (148-24-3) and its sulfate (134-31-6)
  • Permited at concentrations equal to or less than 0.3% as stabilizers for hydrogen peroxide in rinse-off hair-care preparations, and 0.03% in leave-on preparations
• Hydroxyzine (68-88-2)
• Hyoscine (51-34-3), its salts and derivatives
• Hyoscyamine (101-31-5), its salts and derivatives
• Hyoscyamus niger L. leaves, seeds, powder, and galenical preparations
• 3-Imidazol-4-ylacrylic acid (104-98-3) and its ethyl ester (urocanic acid (108-98-3))
• Imperatorin (482-44-0)
• Inproquone (436-40-8)
• Inula helenium oil (97676-35-2)
• Iodine (7553-56-2)
• Isocarboxazide (59-63-2)
• Isodrin (465-73-6)
• Isometheptene (503-01-5) and its salts
• Isophorone (78-59-1)
• Isoprenaline (7683-59-2)
• Isopropamide (N-(3-carbamoyl-3,3-diphenylpropyl)-N,N-diisopropylmethylammonium) salts
• 6-Isopropyl-2-decahydronaphthalenol (34131-99-2)
• Isosorbide dinitrate (87-33-2)
• Juniperus sabina L. leaves, essential oil (68916-94-9) and galenical preparations
• Keratin (see "Human origin, substances of" and/or "Bovine tissues and ingredients")
• Laurus nobilis L., oil (8007-48-5) from the seeds of
• Lead (7439-92-1) and its compounds
• Lead acetate (301-04-2)
• Levophacetoperane (24558-01-8) and its salts
• Lidocaine (137-58-6)
• Lindane (58-89-9)
• Lobelia inflata L. and its galenical preparations
• Lobeline (90-69-7) and its salts
• Lysergide (50-37-3) and its salts

• A-C
• D-L
• M-P
• Q-Z