Health Canada
Symbol of the Government of Canada

Common menu bar links

Drugs and Health Products

Index of Published Newsletters

The Health Product InfoWatch

April 2017

March 2017

February 2017

January 2017

December 2016

November 2016

October 2016

September 2016

August 2016

July 2016

June 2016

May 2016

April 2016

March 2016

February 2016

January 2016

December 2015

November 2015

October 2015

September 2015

August 2015

July 2015

June 2015

May 2015

April 2015

March 2015

February 2015

January 2015

Canadian Adverse Reaction Newsletters

October 2014; 24(4)

July 2014; 24(3)

April 2014; 24(2)

January 2014; 24(1)

October 2013; 23(4)

July 2013; 23(3)

April 2013; 23(2)

January 2013; 23(1)

October 2012; 22(4)

July 2012; 22(3)

April 2012; 22(2)

January 2012; 22(1)

October 2011; 21(4)

July 2011; 21(3)

April 2011; 21(2)

January 2011; 21(1)

October 2010; 20(4)

July 2010; 20(3)

April 2010; 20(2)

January 2010; 20(1)

October 2009; 19(4)

July 2009; 19(3)

April 2009; 19(2)

January 2009; 19(1)

October 2008; 18(4)

July 2008; 18(3)

April 2008; 18(2)

January 2008; 18(1)

October 2007; 17(4)

July 2007; 17(3)

April 2007; 17(2)

January 2007; 17(1)

October 2006; 16(4)

July 2006; 16(3)

April 2006; 16(2)

January 2006; 16(1)

October 2005; 15(4)

July 2005; 15(3)

April 2005; 15(2)

January 2005; 15(1)

October 2004; 14(4)

July 2004; 14(3)

April 2004; 14(2)

January 2004; 14(1)

October 2003; 13(4)

July 2003; 13(3)

April 2003; 13(2)

January 2003; 13 (1)

October 2002; 12 (4)

July 2002; 12 (3)

April 2002; 12 (2)

January 2002; 12 (1)

October 2001; 11(4)

July 2001; 11(3)

April 2001; 11(2)

January 2001; 11(1)

October 2000; 10(4)

July 2000; 10 (3)

April 2000; 10 (2)

January 2000; 10 (1)

October 1999;9(4)

  • Serious hematologic reactions associated with ticlopidine - update
  • Leukotriene receptor antagonists: suspected adverse reactions
  • Communiqué - Ropinirole (Requip): sleep disorder

July 1999; 9(3)

  • Alteplase (Activase rt-PA) for acute ischemic stroke
  • Abciximab (ReoPro): risk of acute thrombocytopenia
  • Nefazodone (Serzone) and hepatotoxicity
  • Communiqué - Amlodipine (Norvasc): hearing loss

April 1999; 9(2)

  • Bupropion (Zyban): suspected adverse reactions
  • 1998 ADR Statistics
  • Updates: immune globulin IV products, tolcapone (Tasmar)
  • Communiqué - Olanzapine (Zyprexa): priapism

January 1999; 9(1)

  • Isotretinoin and depression
  • Low-dose ASA and GI Bleeding
  • Guidelines for reporting ADRs
  • Communiqué - azithromycin, pentoxifylline, sertraline and carbamazepine: interaction

October 1998; 8(4)

  • Recent News About Drug Risks
  • New Ontario Regional ADR Centre
  • Discontinuation Reactions Associated With SSRIs
  • Communiqué - amantadine and warfarin, pantoprazole

July 1998; 8(3)

  • Quality Information in Spontaneous Reports
  • Donepezil: Suspected Adverse Reactions
  • Olanzapine: Hematological Reactions
  • Communiqué - valproic acid, cefaclor, latanoprost, protease inhibitors

April 1998; 8(2)

  • Alendronate-induced esophagitis
  • 1997 ADR statistics
  • Communiqué - dorzolamide hydrochloride, hydroxychloroquine sulfate, torvastatin calcium, risperidone, venlafaxine hydrochloride

January 1998; 8(1)

  • Drugs: QT interval prolongation and torsades de pointes
  • Ciprofloxacin use in epileptic patients taking phenytoin
  • Appetite suppressants - update
  • Communiqué - vigabatrin, mefloquine, lamotrigine

October 1997; 7(4)

  • Calcium-channel blockers
  • Azithromycin - severe iatrogenic hepatitis
  • Newsletter survey results
  • Communiqué - protease inhibitors, vigabatrin, terconazole, Fen-phen, heparin, paroxetine

July 1997; 7(3)

  • ACE inhibitors and bronchospasm
  • Interferon beta-1b
  • Radiopharmaceuticals
  • New Expert Advisory Committee on Pharmacovigilance

April 1997; 7(2)

  • Adverse drug reaction reporting - 1996
  • Potential abuse of butorphanol nasal spray
  • Aminoglycoside ear drops and ototoxicity

January 1997; 7(1)

  • Primary pulmonary hypertension and appetite suppressants
  • HIV protease inhibitors and increased bleeding in hemophilia?
  • Erythema multiforme and nifedipine
  • Congenital anomalies and fluconazole

October 1996; 6(4)

  • Cefaclor-associated serum sickness-like reaction
  • Newsletter Assessment - Questionnaire

July 1996; 6(3)

  • Cisapride: Arrhythmia Awareness
  • Midazolam: A Wake-Up Call
  • Clarithromycin: Tooth Discolouration and Smell Alteration

April 1996; 6(2)

  • Metformin: Lactic Acidosis
  • Nefazodone: ADR Profile
  • 1995 Statistics ADR or Product Fault?

January 1996; 6(1)

  • Cotrimoxazole
  • Nicotine Patches and exercise
  • Terbinafine - hepatobiliary reactions
  • SSRIs - hyponatremia

October 1995; 5(4)

  • Update: Fertility Drugs
  • Propofol: Convulsions
  • Contraindications: Dinoprostone
  • Vaginal Gel
  • DOCI List

July 1995; 5(3)

  • Reporting Adverse Drug Reactions
  • Lamotrigine (Lamictal): rashes
  • Drug Names: confusion from two fronts
  • Tiaprofenic Acid: cystitis
  • Ticlopidine: revisited
  • DOCI List

April 1995; 5(2)

  • Zidovudine: Benefits of use during pregnancy
  • Serevent®: Patient warnings must be stressed
  • Fluoroquinolones: Tendonitis
  • Topical Antifungals: Recent switch to over-the-counter
  • Phenazopyridine: Hemolytic anemia

January 1995; 5(1)

  • Risperidone and EPS Sumatriptan and migraine exacerbation
  • Bromocriptine
  • Fertility drug awareness
  • New regional centre for Quebec

October 1994; 4(3)

  • Regional Centres
  • New Drugs - Serzone, Neurontin, Sabril
  • Drugs of current interest

July 1994; 4(2)

  • Editorial Note
  • Terbinafine Herbal preparations

March 1994; 4(1)

  • Rhabdomyolysis and HMG-CoA
  • Reductase Inhibitors
  • Antidepressants and Suicide
  • Help Wanted: Risperdal

November 1993; 3(2)

  • Ticlopidine HCl - Hematological and Liver Effects
  • H1-Antihistamines - Cardiotoxic Effects

August 1993; 3(1)

  • ACE Inhibitors: Renal Effects
  • Sumatriptan Succinate: Chest Pain
  • Nicotine Patches: Update / Inadvertent Exposure

April 1992; 2(1)

  • ADR Program, 1991 Annual Report
  • Case Report: Drug Interactions with Omeprazole
  • Vasospasm with B-Blockers
  • GI Bleeding with Toradol®

August 1991; 1(2)

  • PPSP Workshop Minocycline - Case reports of severe liver and renal reactions
  • ADRs in the Elderly Ciprofloxacin - ADR profile Diclofenac - Hepatic reactions

January 1991; 1(1)

  • Saskatchewan ADR Pilot Project
  • The WHO Connection Working Group on ADR Assessment