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Long description - Guidance Document: Conduct and Analysis of Comparative Bioavailability Studies

  1. Intra-subject coefficient of variation equals 100 times open first bracket e to the power of open second bracket the mean square residual close second bracket minus 1 close first bracket to the power of 0.5 equals 100 times open first bracket e to the power of open second bracket 0.0729 close second bracket minus 1 close first bracket to the power of 0.5 equals 27.49 percent
  2. Inter-subject coefficient of variation equals 100 times open first bracket e to the power of open second bracket the mean square subject nested within sequence close second bracket minus 1 close first bracket to the power of 0.5 equals 100 times open first bracket e to the power of open second bracket 0.2648 close second bracket minus 1 close first bracket to the power of 0.5 equals 55.06 percent
  3. where the mean square residual equals the mean square residual and the mean square subject nested within sequence equals the mean square subject nested within sequence