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Home > Environmental & Workplace Health > Environmental Contaminants > Existing Substances > Categorization of Substances on the Domestic Substances List > Results of the Health-Related Components of Categorization of the Domestic Substances List under CEPA 1999

Environmental and Workplace Health

Results of the Health-Related Components of Categorization of the Domestic Substances List under CEPA 1999

Table of Contents

High Health Priorities for Action

July 27, 2006

         : Health Canada "Categorized In" Substances

Results based on July 27, 2006 and persistent and bioaccumulative status as of July 2006
ID CAS RN Chemical Name Maximal List Subgroup Status SimHaz Result
Carcinogenicity1		 SimHaz Result
Developmental Toxicity2		 SimHaz Result
Genotoxicity3		 SimHaz Result
Reproductive Toxicity4
1 62-56-6 Thiourea High - GPE GPE X X    
2 74-87-3 Methane, chloro- High - GPE GPE X      
3 75-28-5 Propane, 2-methyl- High - GPE GPE X   X  
4 75-56-9 Oxirane, methyl- High - GPE GPE X   X  
5 78-59-1 2-Cyclohexen-1-one, 3,5,5-trimethyl- High - GPE GPE X      
6 78-79-5 1,3-Butadiene, 2-methyl- High - GPE GPE X   X  
7 79-06-1 2-Propenamide High - GPE GPE X   X X
8 80-05-7 Phenol, 4,4 -(1-methylethylidene)bis- High - GPE GPE       X
9 91-20-3 Naphthalene High - GPE GPE X      
10 96-29-7 2-Butanone, oxime High - GPE GPE X      
11 98-01-1 2-Furancarboxaldehyde High - GPE GPE X      
12 100-41-4 Benzene, ethyl- High - GPE GPE X      
13 100-44-7 Benzene, (chloromethyl)- High - GPE GPE X      
14 103-23-1 Hexanedioic acid, bis(2-ethylhexyl) ester High - GPE GPE X      
15 106-89-8 Oxirane, (chloromethyl)- High - GPE GPE X      
16 106-97-8 Butane High - GPE GPE X   X  
17 108-05-4 Acetic acid ethenyl ester High - GPE GPE X      
18 110-54-3 Hexane High - GPE GPE   X   X
19 111-15-9 Ethanol, 2-ethoxy-, acetate High - GPE GPE   X   X
20 111-77-3 Ethanol, 2-(2-methoxyethoxy)- High - GPE GPE   X    
21 123-31-9 1,4-Benzenediol High - GPE GPE X   X  
22 123-91-1 1,4-Dioxane High - GPE GPE X      
23 140-88-5 2-Propenoic acid, ethyl ester High - GPE GPE X      
24 149-57-5 Hexanoic acid, 2-ethyl- High - GPE GPE   X    
25 630-08-0 Carbon monoxide High - GPE GPE   X    
26 1309-64-4 Antimony oxide (Sb2O3) High - GPE GPE X      
27 1314-62-1 Vanadium oxide (V2O5) High - GPE GPE X X X  
28 1333-86-4 Carbon black High - GPE GPE X      
29 1344-37-2 C.I. Pigment Yellow 34 High - GPE GPE X X   X
30 7440-48-4 Cobalt High - GPE GPE X      
31 10124-43-3 Sulfuric acid, cobalt(2+) salt (1:1) High - GPE GPE X      
32 12656-85-8 C.I. Pigment Red 104 High - GPE GPE X X   X
33 14464-46-1 Cristobalite (SiO2) High - GPE GPE X      
34 14808-60-7 Quartz (SiO2) High - GPE GPE X      
35 26471-62-5 Benzene, 1,3-diisocyanatomethyl- High - GPE GPE X      
36 68391-11-7 Pyridine, alkyl derivs. High - GPE GPE X      
37 64-67-5 Sulfuric acid, diethyl ester High - IPE IThuman + P or B X   X  
38 75-12-7 Formamide High - IPE Other High Health Priority   X    
39 75-52-5 Methane, nitro- High - IPE IThuman + P or B X      
40 77-78-1 Sulfuric acid, dimethyl ester High - IPE Other High Health Priority X   X  
41 79-07-2 Acetamide, 2-chloro- High - IPE Other High Health Priority       X
42 79-46-9 Propane, 2-nitro- High - IPE IThuman + P or B X      
43 87-86-5 Phenol, pentachloro- High - IPE IThuman + P or B X      
44 88-12-0 2-Pyrrolidinone, 1-ethenyl- High - IPE Other High Health Priority X      
45 88-72-2 Benzene, 1-methyl-2-nitro- High - IPE IThuman + P or B X X X X
46 90-94-8 Methanone, bis[4-(dimethylamino)phenyl]- High - IPE IThuman + P or B X   X  
47 91-08-7 Benzene, 1,3-diisocyanato-2-methyl- High - IPE Other High Health Priority X      
48 93-15-2 Benzene, 1,2-dimethoxy-4-(2-propenyl)- High - IPE Other High Health Priority X      
49 101-14-4 Benzenamine, 4,4'-methylenebis[2-chloro- High - IPE IThuman + P or B X      
50 102-06-7 Guanidine, N,N -diphenyl- High - IPE IThuman + P or B   X   X
51 106-88-7 Oxirane, ethyl- High - IPE IThuman + P or B X      
52 106-93-4 Ethane, 1,2-dibromo- High - IPE IThuman + P or B X      
53 107-05-1 1-Propene, 3-chloro- High - IPE Other High Health Priority X   X  
54 107-22-2 Ethanedial High - IPE Other High Health Priority     X  
55 110-49-6 Ethanol, 2-methoxy-, acetate High - IPE Other High Health Priority   X   X
56 115-96-8 Ethanol, 2-chloro-, phosphate (3:1) High - IPE IThuman + P or B X      
57 117-82-8 1,2-Benzenedicarboxylic acid, bis(2-methoxyethyl) ester High - IPE Other High Health Priority   X   X
58 120-80-9 1,2-Benzenediol High - IPE Other High Health Priority X      
59 126-73-8 Phosphoric acid tributyl ester High - IPE IThuman + P or B X      
60 127-19-5 Acetamide, N,N-dimethyl- High - IPE Other High Health Priority   X    
61 139-13-9 Glycine, N,N-bis(carboxymethyl)- High - IPE IThuman + P or B X      
62 302-01-2 Hydrazine High - IPE Other High Health Priority X      
63 330-54-1 Urea, N'-(3,4-dichlorophenyl)-N,N-dimethyl- High - IPE IThuman + P or B X      
64 534-52-1 Phenol, 2-methyl-4,6-dinitro- High - IPE IThuman + P or B     X  
65 556-67-2 Cyclotetrasiloxane, octamethyl- High - IPE IThuman + P or B   X   X
66 584-84-9 Benzene, 2,4-diisocyanato-1-methyl- High - IPE Other High Health Priority X      
67 1589-47-5 1-Propanol, 2-methoxy- High - IPE Other High Health Priority   X    
68 2426-08-6 Oxirane, (butoxymethyl)- High - IPE Other High Health Priority X   X  
69 7646-79-9 Cobalt chloride (CoCl2) High - IPE IThuman + P or B X      
70 7758-01-2 Bromic acid, potassium salt High - IPE IThuman + P or B X      
71 25013-16-5 Phenol, (1,1-dimethylethyl)-4-methoxy- High - IPE Other High Health Priority X      
72 68515-42-4 1,2-Benzenedicarboxylic acid, di-C7-11-branched and linear alkyl esters High - IPE Other High Health Priority   X   X
73 50-18-0 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-,2-oxide High - FDA Other High Health Priority X      
74 55-86-7 Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-, hydrochloride High - FDA Other High Health Priority X      
75 55-98-1 1,4-Butanediol, dimethanesulfonate High - FDA Other High Health Priority X      
76 57-41-0 2,4-Imidazolidinedione, 5,5-diphenyl- High - FDA Other High Health Priority X      
77 68-22-4 19-Norpregn-4-en-20-yn-3-one, 17-hydroxy-, (17αa)- High - FDA Other High Health Priority X      
78 126-07-8 Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'S,6'R)- High - FDA Other High Health Priority X      
79 148-82-3 L-Phenylalanine, 4-[bis(2-chloroethyl)amino]- High - FDA Other High Health Priority X      
80 154-93-8 Urea, N,N'-bis(2-chloroethyl)-N-nitroso- High - FDA Other High Health Priority X      
81 305-03-3 Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]- High - FDA Other High Health Priority X      
82 443-48-1 1H-Imidazole-1-ethanol, 2-methyl-5-nitro- High - FDA Other High Health Priority X      
83 446-86-6 1H-Purine, 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]- High - FDA Other High Health Priority X      
84 6804-07-5 Hydrazinecarboxylic acid, [(1,4-dioxido-2-quinoxalinyl)methylene]-, methyl ester High - FDA Other High Health Priority X      
85 7446-34-6 Selenium sulfide High - FDA IThuman + P or B X      
86 10540-29-1 Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethyl- High - FDA IThuman + P or B X      
87 13010-47-4 Urea, N-(2-chloroethyl)-N'-cyclohexyl-N-nitroso- High - FDA Other High Health Priority X      
88 18883-66-4 D-Glucose, 2-deoxy-2-[[(methylnitrosoamino)carbonyl]amino]- High - FDA Other High Health Priority X      
89 20830-81-3 D-Glucose, 2-deoxy-2-[[(methylnitrosoamino)carbonyl]amino]- High - FDA Other High Health Priority X      
90 29767-20-2 Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[[4,6-O-[(R)-2-thienylmethylene]-β-D-glucopyranosyl]oxy]-, (5R,5aR,8aR,9S)- High - FDA Other High Health Priority X      
91 33419-42-0 Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-α-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahy dro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, High - FDA Other High Health Priority X      
92 51264-14-3 Methanesulfonamide, N-[4-(9-acridinylamino)-3-methoxyphenyl]- High - FDA Other High Health Priority X      
93 59865-13-3 Cyclosporin A High - FDA IThuman + P or B X      
94 50-06-6 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl- High - LPE Other High Health Priority X      
95 51-79-6 Carbamic acid, ethyl ester High - LPE Other High Health Priority X      
96 55-18-5 Diethylnitrosamine High - LPE Other High Health Priority X      
97 56-75-7 Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]- High - LPE Other High Health Priority X      
98 58-89-9 Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1α,2α,3β,4α,5α,6β)- High - LPE IThuman + P or B X      
99 59-88-1 Hydrazine, phenyl-, monohydrochloride High - LPE Other High Health Priority X   X  
100 60-09-3 Benzenamine, 4-(phenylazo)- High - LPE Other High Health Priority X      

B - bioaccumulation/bioaccumulative
CAS RN - Chemical Abstracts Registry Number
FDA - Food and Drugs Act substances in commerce in 1984-1986 which were added to the DSL
GPE - Greatest Potential for Exposure
IPE - Intermediate Potential for Exposure
IThuman - inherently toxic to humans
LPE - Lowest Potential for Exposure
P - persistence/persistent
SimHaz - Simple Hazard Tool

Table of Contents
Date Modified: 2008-01-31

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