Health Canada
Symbol of the Government of Canada
Environmental and Workplace Health

State of the Science Report for MBMBP

References

ACC (American Cyanamid Company). 1965a. IUCLID (International Uniform Chemical Information Database), 1996 [cited in OECD, 2003a].

ACC (American Cyanamid Company). 1965b. Antioxidant 2246: Ninety-day repeated feeding to dogs (Report No. 65-135).

ACC (American Cyanamid Company). 1988. IUCLID (International Uniform Chemical Information Database), 1996 [cited in OECD, 2003a].

Ashland Oil Inc. 1992. Initial submission: toxicity report on 2,2'-(4-methyl-6-tertiary-butylphenol) with cover letter dated 10/15/92. Report prepared for DuPont Chemicals. Submitted to U.S. Environmental Protection Agency (NTIS/OTS0571632; Document No. 88-920009974).

Bayer AG. 1988. IUCLID (International Uniform Chemical Information Database), 1996 [cited in OECD, 2003a].

EHD (Environmental Health Directorate). 1998. Exposure factors for assessing total daily intake of Priority Substances by the general population of Canada. Unpublished report. Priority Substances Section, Environmental Health Directorate, Health Canada, Ottawa, Ontario.

Next link will take you to another Web site Environment Canada. 2001. Canadian Environmental Protection Act, 1999. Notice with respect to certain substances on the Domestic Substances List (DSL). Canada Gazette, Part I, 135(46): 4194-4211 (PDF Version - 575 k). http://canadagazette.gc.ca/partI/2001/20011117/pdf/g1-13546.pdf.

Next link will take you to another Web site European Communities. 2003. European Commission technical guidance document on risk assessment: Part II. European Chemicals Bureau, Institute for Health and Consumer Protection, Joint Research Centre, European Commission (http://ecb.jrc.it/existing-chemicals/).

Hagan, E.C. 1952. Oral toxicity of 2,2' methylene bis (4 methyl-6-tertiary-butylphenol) (2246). Fed. Proc. 11: 353.

Next link will take you to another Web site Mackay, D., Di Guardo, A., Paterson, S. and Tam, D.D. 1996. ChemCAN 4: Level III fugacity model of regional fate of chemicals. Version 4.95. University of Toronto, Toronto, Ontario (http://www.trentu.ca/cemc/models/ChemCAN.html).

MHW (Ministry of Health and Welfare Japan). 1996. Toxicity Testing Report of Environmental Chemicals 4. pp. 409-430 [cited in OECD, 2003a].

MHW (Ministry of Health and Welfare Japan). 1999. Toxicity Testing Report of Environmental Chemicals 7. pp. 423-437 [cited in OECD, 2003a].

Next link will take you to another Web site NCI (National Cancer Institute). 1993. 2,2-Methylenebis (4-methyl-6-tert-butylphenol). Chemical Carcinogenesis Research Information System (CCRIS) Record No. 4919. Last update: 10/09/93. Database searched on January 31, 2000 (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CCRIS).

NHW (Department of National Health and Welfare). 1990. Present patterns and trends in infant feeding in Canada. Department of National Health and Welfare, Ottawa, Ontario. 9 pp. (Catalogue No. H39-199/1990E; ISBN 0-662-18397-5) [cited in EHD, 1998].

Next link will take you to another Web site NLM (National Library of Medicine). 1998. Bis (2-hydroxy-3-tert-butyl-5-methylphenyl)methane. Hazardous Substances Data Bank. Last update: 06/03/98. Database searched on January 27, 2000 (http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB).

Next link will take you to another Web site OECD (Organisation for Economic Co-operation and Development). 2003a. SIDS initial assessment report: 6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol. Vol. 9/1. UNEP Publications. Accessed July 2003 (http://www.chem.unep.ch/irptc/Publications/sidsidex/sidsidex.htm).

OECD (Organisation for Economic Co-operation and Development). 2003b. OECD emission scenario document on plastic additives. Revised edition. OECD Environmental Health and Safety Publications: Series on Emission Scenario Documents, Environment Directorate. July 2003.

Stasenkova, K.P. et al. 1977. Kauch Rezina 1: 24-26 [cited in NLM, 1998; OECD, 2003a].

Sumitomo Chemical Co. 1977a. Unpublished report on acute oral toxicity in rats (CC-77-106) [cited in OECD, 2003a].

Sumitomo Chemical Co. 1977b. Unpublished report on Ames test and rec-assay [cited in OECD, 2003a].

Takagi, A., Takada, K., Sai, K., Ochiai, T., Matsumoto, K., Sekita, K., Momma, J., Aida, Y., Saitoh, M., Naitoh, K., Furuya, T., Hasegawa, R. and Kurokawa, Y. 1994. Acute, subchronic and chronic toxicity studies of a synthetic antioxidant, 2,2'-methylenebis (4-methyl-6-tert-butylphenol) in rats. J. Toxicol. Sci. 19: 77-89.

Takahashi, O. and Hiraga, K. 1981a. Effects of four bisphenolic antioxidants on prothrombin levels of rat plasma. Toxicol. Lett. 7: 405-408.

Takahashi, O. and Hiraga, K. 1981b. Effects of four bisphenolic antioxidants on lipid contents of rat liver. Toxicol. Lett. 8: 77-86.

Tanaka, S. et al. 1990. Eisei Shikensho Hokoku 108: 52-57 [cited in OECD, 2003a].

Telford, I.R., Woodruff, C.S. and Linford, L.H. 1962. Fetal resorption in the rat as influenced by certain antioxidants. Am. J. Anat. 110: 29-36.

Tsuchiya, T., Fukuhara, K., Hata, H., Ikarashi, Y., Miyata, N., Katoh, F., Hiroshi, Y. and Nakamura, A. 1995. Studies on the tumour-promoting activity of additives in biomaterials: inhibition of metabolic cooperation by phenolic antioxidants involved in rubber materials. J. Biomed. Mater. Res. 29: 121-126.

Next link will take you to another Web site U.S. EPA (United States Environmental Protection Agency). 2003. Estimation Program Interface (EPI) Suite (EPI Suite™). Version 3.11. June 10, 2003. Models developed by the U.S. EPA Office of Pollution Prevention and Toxics and Syracuse Research Corporation (http://www.epa.gov/opptintr/exposure/docs/episuite.htm).

Yamaguchi, T., Yamauchi, A., Yamazaki, H. and Kakiuchi, Y. 1991. Eisei Kagaku 37(1): 6-13 [cited in NCI, 1993; OECD, 2003a].