Priority Substances List Assessment Report- 1,3-Butadiene

List of Acronyms and Abbreviations

BMC₀₅:   the concentration associated with a 5% increase in the benchmark endpoint

BMCL₀₅:   the lower 95% confidence limit for the BMC₀₅

CAS:   Chemical Abstracts Service

CEPA:   Canadian Environmental Protection Act

CEPA 1999:   Canadian Environmental Protection Act, 1999

CFC:   chlorofluorocarbon

CI:   confidence interval

CTV:   Critical Toxicity Value

DEB:   1,2,3,4-diepoxybutane

DNA:   deoxyribonucleic acid

EB:   1,2-epoxy-3-butene

EBdiol:   1,2-dihydroxy-3,4-epoxybutane

EC₅₀:   median effective concentration

EEV:   Estimated Exposure Value

EH:   epoxide hydrolase

ENEV:   Estimated No-Effects Value

EPI:   Exposure Potency Index

ETS:   environmental tobacco smoke

GSH:   glutathione

GT:   glutathione transferase

GWP:   Global Warming Potential

K_ow:   octanol/water partition coefficient

LC₅₀:   median lethal concentration

LCL:   lower confidence limit

LOEC:   Lowest-Observed-Effect Concentration

LOEL:   Lowest-Observed-Effect Level

MATC:   Maximum Acceptable Toxicant Concentration

MIR:   Maximum incremental reactivity

NAPS:   National Air Pollution Surveillance

NOEC:   No-Observed-Effect Concentration

NO_X:   nitrogen oxides

NPRI:   National Pollutant Release Inventory

NTP:   National Toxicology Program

O:   observed cases

ODP:   Ozone Depletion Potential

OR:   odds ratio

PBPK:   physiologically based pharmacokinetic

POCP:   photochemical ozone creation potential

PSL:   Priority Substances List

QSAR:   quantitative structure-activity relationship

RR:   relative risk

RTECS:   Registry of Toxic Effects of Chemical Substances

SE:   standard error

SMR:   standardized mortality ratio

TC₀₁:   tumorigenic concentration associated with a 1% increase in the incidence of or mortality due to cancer

TC₀₅:   tumorigenic concentration associated with a 5% increase in the incidence of or mortality due to cancer

VOC:   volatile organic compound