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Priority Substances List Assessment Report for 2-Methoxyethanol

Environment Canada
Health Canada
2002
ISBN: 0-662-33596-1
Cat. No.: En40-215/65E

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(PDF Version - 312 K)

Canadian Environmental Protection Act 1999

Table of Contents

• List of Acronyms and Abbreviations
• Synopsis
• 1.0 Introduction
• 2.0 Summary of Information Critical to Assessment of "Toxic" Under CEPA 1999
  • 2.1 Identity and physical/chemical properties
  • 2.2 Entry characterization
    • 2.2.1 Production, importation and uses
    • 2.2.2 Sources and releases
      • 2.2.2.1 Natural sources
      • 2.2.2.2 Anthropogenic sources
  • 2.3 Exposure characterization
    • 2.3.1 Environmental fate
      • 2.3.1.1 Air
      • 2.3.1.2 Surface Water
      • 2.3.1.3 Groundwater
      • 2.3.1.4 Soils
      • 2.3.1.5 Biota
      • 2.3.1.6 Environmental distribution
    • 2.3.2 Environmental concentrations
      • 2.3.2.1 Multimedia exposure study
      • 2.3.2.2 Ambient air
      • 2.3.2.3 Indoor air
      • 2.3.2.4 Surface water
      • 2.3.2.5 Drinking water
      • 2.3.2.6 Soil
      • 2.3.2.7 Food
      • 2.3.2.8 Consumer products
      • 2.3.2.9 Fugacity modelling
  • 2.4 Effects characterization
    • 2.4.1 Ecotoxicology
      • 2.4.1.1 Terrestrial organisms
      • 2.4.1.2 Aquatic organisms
    • 2.4.2 Experimental animals and in vitro
      • 2.4.2.1 Kinetics and metabolism
      • 2.4.2.2 Acute toxicity
      • 2.4.2.3 Short-term toxicity
      • 2.4.2.4 Subchronic toxicity
        • 2.4.2.4.1 Oral
        • 2.4.2.4.2 Inhalation
        • 2.4.2.4.3 Dermal
      • 2.4.2.5 Chronic toxicity and carcinogenicity
      • 2.4.2.6 Genotoxicity
        • 2.4.2.6.1 In vitro studies
        • 2.4.2.6.2 In vivo studies
      • 2.4.2.7 Developmental toxicity
        • 2.4.2.7.1 Oral
        • 2.4.2.7.2 Inhalation
        • 2.4.2.7.3 Dermal
      • 2.4.2.8 Reproductive toxicity
        • 2.4.2.8.1 Reproductive effects in males
        • 2.4.2.8.2 Reproductive effects in females
      • 2.4.2.9 Immunotoxicity
      • 2.4.2.10 Neurotoxicity
    • 2.4.3 Humans
      • 2.4.3.1 Case reports
      • 2.4.3.2 Clinical studies
      • 2.4.3.3 Epidemiological studies
    • 2.4.4 Abiotic atmospheric effects
• 3.0 Aseessment oF "TOXIC" Under CEPA 1999
  • 3.1 CEPA 1999 64(a): Environment
    • 3.1.1 Assessment endpoints
    • 3.1.2 Environmental risk assessment
      • 3.1.2.1 Terrestrial organisms
        • 3.1.2.1.1 Wildlife
        • 3.1.2.1.2 Soil organisms
      • 3.1.2.2 Aquatic organisms
      • 3.1.2.3 Discussion of uncertainty
  • 3.2 CEPA 1999 64(b): Environment upon which life depends
  • 3.3 CEPA 1999 64(c): Human health
    • 3.3.1 Estimates of potential exposure in humans
    • 3.3.2 Human health risk characterization
    • 3.3.3 Uncertainties and degree of confidence in the human health risk characterization
  • 3.4 Conclusions
  • 3.5 Considerations for follow-up (further action)
• 4.0 References
• Appendix A Search Strategies Employed for Identification of Relevant Data

List of Tables

• Table 1 - Worst-case/bounding estimates of intake of 2-methoxyethanol by adult Canadians