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Environmental and Workplace Health

Priority Substances List Assessment Report for N,N-Dimethylformamide

List of Acronyms and Abbreviations

ACN : acrylonitrile

ALT : alanine aminotransferase

AMCC : N-acetyl-S-(N-methylcarbamoyl)cysteine

AP : alkaline phosphatase

AST : aspartate aminotransferase

BMC05 : concentration estimated to cause a 5% increase in incidence over background response rate

BMD : benchmark dose

CA : chromosomal aberration

CAS : Chemical Abstracts Service

CEPA : Canadian Environmental Protection Act

CEPA 1999 : Canadian Environmental Protection Act, 1999

CFC : chlorofluorocarbon

CHO : Chinese hamster ovary

CI : confidence interval

CTV : Critical Toxicity Value

DMF : N,N-dimethylformamide

EC50 : median effective concentration

ECG : electrocardiograph

EEV : Estimated Exposure Value

ENEV : Estimated No-Effects Value

gamma-GT : gamma-glutamyl transpeptidase

GWP : Global Warming Potential

HMMF : N-(hydroxymethyl)-N-methylformamide

IC50 : median inhibitory concentration

Koc : organic carbon/water partition coefficient

Kom : soil sorption coefficient

Kow : octanol/water partition coefficient

kg-bw : kilogram body weight

LC50 : median lethal concentration

LCL05 : lower confidence limit of the BMC05

LD50 : median lethal dose

LOAEC : Lowest-Observed-Adverse-Effect Concentration

LOAEL : Lowest-Observed-Adverse-Effect Level

LOEC : Lowest-Observed-Effect Concentration

LOEL : Lowest-Observed-Effect Level

NMF : N-methylformamide

NOAEL : No-Observed-Adverse-Effect Level

NOEC : No-Observed-Effect Concentration

NOEL : No-Observed-Effect Level

ODP : Ozone Depletion Potential

POCP : Photochemical Ozone Creation Potential

PSL : Priority Substances List

PVC : polyvinyl chloride

SCE : sister chromatid exchange

SGOT : serum glutamate-oxalate transaminase

SGPT : serum glutamate-pyruvate transaminase

SIR : standardized incidence rate

TC : Tolerable Concentration

TWA : time-weighted average

UDS : unscheduled DNA synthesis

VOC : volatile organic compound