Science Publications

In this section you will find summaries of research projects recently completed by scientists and researchers within Health Canada. The results of federal research, aimed at protecting the health of Canadians and their environments, will contribute to evidence-based decision making, programs and/or policy. This site will be periodically updated with information on the latest research coming out of the Department.

Acoustics

• MP3 Player Listening Sound Pressure Levels among 10 to 17 year old Students

Air

• Residential Indoor and Outdoor Coarse Particles and Associated Endotoxin Exposures
• Urinary Polycyclic Aromatic Hydrocarbons as a Biomarker of Exposure to PAHS in Air: A Pilot Study among Pregnant Women
• Traffic-Related Air Pollution and Acute Changes in Heart Rate Variability and Respiratory Function in Urban Cyclists
• Windsor, Ontario Exposure Assessment Study: Design and Methods Validation of Personal, Indoor and Outdoor Air Pollution Monitoring
• Back-Extrapolation of Estimates of Exposure from Current Land-Use Regression Model
• Evaluation of Land-Use Regression Models Used to Predict Air Quality Concentrations in an Urban Area
• Buoyancy-Corrected Gravimetric Analysis of Lightly Loaded Filters
• Concentration Distribution and Bioaccessibility of Trace Elements in Nano and Fine Urban Airborne Particulate Matter: Influence of Particle Size
• Hepatic mRNA, microRNA, and miR-34a-Target Responses in Mice after 28 Exposure to Doses of Benzo(a)pyrene that Elicit DNA Damage and Mutation
• Spatial Distribution of Polycyclic Aromatic Hydrocarbons (Pahs) in an Urban Environment
• Germline Mutation Rates in Mice Following in Utero Exposure to Diesel Exhaust Particles by Maternal Inhalation
• Physical-Chemical and Microbiological Characterization, and Mutagenic Activity of Airborne Pm Sampled in A Biomass-Fueled Electrical Production Facility

Biotechnology

• Early Murine Immune Responses from Endotracheal Exposures to Biotechnology-Related Bacillus Strains

Chemicals

• Phthalates in Cosmetic and Personal Care Products: Concentrations and Possible Dermal Exposure
• Thyroid Hormone-Regulated Gene Expression in Juvenile Mouse Liver: Identification of Thyroid Response Elements Using Microarray Profiling and in Silico Analyses
• Simultaneous Measurement of Benzo[A]Pyrene-Induced Pig-A and Lacz Mutations, Micronuclei And DNA Adducts in Muta Mouse
• Barhl1 is directly Regulated by Thyroid Hormone in the Developing Cerebellum of Mice
• Pulmonary Gene and Microrna Expression Changes in Mice Exposed to Benzo(A)Pyrene by Oral Gavage
• Assessment of Subclinical, Toxicant-Induced Hepatic Gene Expression Profiles after Low-Dose, Short-Term Exposures in Mice
• Polychlorinated Biphenyls (PCBS) Contamination and Aryl Hydrocarbon Receptor (AHR) Agonist Activity of Omega-3 Polyunsaturated Fatty Acid Supplements: Implications for Daily Intake of Dioxins and PCBS
• A Survey of the Traditional Food Consumption that may Contribute to Enhanced Soil Ingestion in a Canadian First Nation Community
• A Soil Ingestion Pilot Study of a Population Following a Traditional Lifestyle Typical of Rural or Wilderness Areas

Nanotechnology

• Carbon Black Nanoparticle Instillation Induces Sustained Inflammation and Genotoxicity in Mouse Lung and Liver
• Pulmonary Response to Surface-Coated Nanotitanium Dioxide Particles Includes Induction of Acute Phase Response Genes, Inflammatory Cascades, and Changes in Micrornas: A Toxicogenomic Study
• Poly(Ethylene Imine) Nanocarriers do not Induce Mutations nor Oxidative DNA Damage In Vitro in Mutamouse Fe1 Cells
• Mutation Spectrum in Fe1-Muta™ Mouse Lung Epithelial Cells Exposed to Nanoparticulate Carbon Black

Radon

• An Update on Thoron Exposure in Canada with Simultaneous 222Rn and 220Rn Measurements in Fredericton and Halifax
• Assessment of Radon Equilibrium Factor from Distribution Parameters of Simultaneous Radon and Radon Progeny Measurements
• Radon Exhalation from Building Materials for Decorative Use

Tobacco

• Assessment of Validity of Self-Reported Smoking Status
• Sidestream Tobacco Smoke is a Male Germ Cell Mutagen
• Genetic Toxicology and Toxicogenomic Analysis of Three Cigarette Smoke Condensates In Vitro Reveals Few Differences Among Full-Flavor, Blonde, and Light Products
• The Analysis of Mainstream Smoke Emissions Of Canadian 'Super Slim' Cigarettes

Water

• Pressure-Assisted Electrokinetic Injection For On-Line Enrichment in Capillary Electrophoresis-Mass Spectrometry: A Sensitive Method for Measurement of Ten Haloacetic Acids in Drinking Water